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Christopher E M Griffiths Selected Research

Biological Therapy

10/2022Drug Survival Associated With Effectiveness and Safety of Treatment With Guselkumab, Ixekizumab, Secukinumab, Ustekinumab, and Adalimumab in Patients With Psoriasis.
5/2022Clinical efficacy and safety of secukinumab in patients with psoriasis and comorbidities: pooled analysis of 4 phase 3 clinical trials.
1/2021Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis.
1/2021Meeting Report: Psoriasis Stratification to Optimize Relevant Therapy Showcase.
1/2020Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study.
1/2019A Framework for Multi-Omic Prediction of Treatment Response to Biologic Therapy for Psoriasis.
1/2019HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis.
8/2018A small population, randomised, placebo-controlled trial to determine the efficacy of anakinra in the treatment of pustular psoriasis: study protocol for the APRICOT trial.
1/2018Risk of Serious Infection in Patients with Psoriasis Receiving Biologic Therapies: A Prospective Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).
1/2018Differential Drug Survival of Second-Line Biologic Therapies in Patients with Psoriasis: Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).
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Christopher E M Griffiths Research Topics

Disease

107Psoriasis (Pustulosis Palmaris et Plantaris)
10/2022 - 01/2002
8Neoplasms (Cancer)
06/2022 - 08/2006
8Infections
01/2021 - 08/2006
7Inflammation (Inflammations)
12/2022 - 08/2006
6Necrosis
02/2015 - 10/2005
5Psoriatic Arthritis
10/2022 - 06/2011
4Atopic Dermatitis (Atopic Eczema)
10/2022 - 09/2008
4Skin Neoplasms (Skin Cancer)
02/2020 - 11/2002
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2022 - 02/2020
3Crohn Disease (Crohn's Disease)
02/2020 - 11/2005
3Systemic Scleroderma (Systemic Sclerosis)
09/2016 - 08/2012
3Rheumatoid Arthritis
05/2015 - 06/2005
3Skin Diseases (Skin Disease)
02/2014 - 02/2004
3Autoimmune Diseases (Autoimmune Disease)
04/2013 - 06/2005
2COVID-19
10/2021 - 01/2021
2Arthritis (Polyarthritis)
01/2021 - 02/2014
2Genetic Predisposition to Disease (Genetic Predisposition)
01/2021 - 01/2019
2Injection Site Reaction
01/2019 - 10/2017
2Eczema
10/2017 - 08/2004
2Telangiectasis (Telangiectasia)
08/2014 - 03/2013
1Cytopenia
06/2022
1Body Weight (Weight, Body)
05/2022
1Obesity
01/2021
1Dementia (Dementias)
01/2021
1Type 2 Diabetes Mellitus (MODY)
01/2021
1Streptococcal Infections (Streptococcal Infection)
01/2021
1Ulcerative Colitis
02/2020
1Rare Diseases (Rare Disease)
08/2018
1Acquired Immunodeficiency Syndrome (AIDS)
01/2018
1Asthma (Bronchial Asthma)
10/2017
1Conjunctivitis
10/2017

Drug/Important Bio-Agent (IBA)

18Biological ProductsIBA
10/2022 - 06/2004
15Ustekinumab (CNTO 1275)FDA Link
10/2022 - 01/2010
14Pharmaceutical PreparationsIBA
10/2022 - 09/2007
13Adalimumab (Humira)FDA Link
10/2022 - 05/2015
12Etanercept (Enbrel)FDA Link
05/2022 - 01/2010
11ixekizumabIBA
10/2022 - 08/2015
10Monoclonal AntibodiesIBA
11/2020 - 06/2004
9Interleukin-17 (Interleukin 17)IBA
01/2022 - 07/2014
8Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2021 - 07/2004
8InterleukinsIBA
08/2021 - 05/2012
7guselkumabIBA
10/2022 - 03/2017
7CytokinesIBA
01/2021 - 07/2004
6secukinumabIBA
10/2022 - 07/2014
6Immunoglobulin A (IgA)IBA
05/2022 - 10/2017
6Methotrexate (Mexate)FDA LinkGeneric
01/2022 - 08/2008
6Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2016
6Interleukin-23 (Interleukin 23)IBA
01/2021 - 01/2010
6Infliximab (Remicade)FDA Link
01/2010 - 10/2005
5Proteins (Proteins, Gene)FDA Link
11/2017 - 06/2007
4Immunologic Factors (Immunomodulators)IBA
10/2022 - 05/2008
4AntibodiesIBA
11/2020 - 02/2014
4RetinoidsIBA
01/2016 - 07/2003
3omega-Chloroacetophenone (Mace)IBA
06/2022 - 03/2012
3apremilastIBA
01/2022 - 07/2015
3HLA-C Antigens (HLA-C)IBA
01/2021 - 11/2010
3Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
11/2020 - 08/2018
3Interleukin-12 (IL 12)IBA
01/2019 - 01/2010
34-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA
03/2013 - 06/2002
2Immunomodulating AgentsIBA
10/2021 - 02/2004
2Tumor Necrosis Factor InhibitorsIBA
10/2021 - 01/2019
2GoldIBA
01/2021 - 08/2011
2bimekizumabIBA
11/2020 - 08/2018
2Prostaglandins AIBA
11/2020 - 01/2018
2levocetirizineFDA LinkGeneric
01/2020 - 01/2020
2Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2018 - 09/2008
2Interleukin-13IBA
10/2017 - 06/2011
2Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
01/2016 - 07/2015
2Anthralin (Dithranol)IBA
08/2015 - 01/2005
2Transcription Factor AP-1 (Transcription Factor AP 1)IBA
05/2014 - 02/2006
2ProlactinIBA
01/2013 - 03/2012
2Immunoglobulin G (IgG)IBA
09/2008 - 06/2007
2AutoantibodiesIBA
09/2008 - 06/2005
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2006 - 01/2004
1Fibronectins (Fibronectin)IBA
12/2022
1FibrillinsIBA
12/2022
1Vitamin A (Retinol)FDA LinkGeneric
12/2022
1ElastinIBA
12/2022
1CollagenIBA
12/2022
1RNA (Ribonucleic Acid)IBA
10/2022
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2022
1Blocking AntibodiesIBA
01/2022
1Immunoglobulins (Immunoglobulin)IBA
01/2022
1Interleukin-23 Subunit p19IBA
08/2021
1Immunosuppressive Agents (Immunosuppressants)IBA
01/2021
1Histamine Antagonists (Antihistamines)IBA
01/2020
1Histamine H1 Receptors (Histamine H1 Receptor)IBA
01/2020
1Histamine (Histamine Dihydrochloride)FDA Link
01/2020
1Interleukin-1 (Interleukin 1)IBA
08/2018
1LipidsIBA
01/2018
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2017
1Interleukin-4 (Interleukin 4)IBA
10/2017
1dupilumabIBA
10/2017

Therapy/Procedure

39Therapeutics
01/2021 - 06/2003
21Biological Therapy
10/2022 - 04/2006
3Photochemotherapy (Photodynamic Therapy)
01/2017 - 06/2003
2Subcutaneous Injections
08/2018 - 01/2010
2Phototherapy (Light Therapy)
01/2017 - 01/2016
2Lasers (Laser)
09/2016 - 08/2014
2Immunotherapy
01/2014 - 01/2002